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Development of Fast Dissolving Tablets   Basavaraj Nanjwade and Sachin A. Thakare

Development of Fast Dissolving Tablets

156 страниц. 2011 год.
LAP Lambert Academic Publishing
Oral drug delivery has been known for decades the most widely utilized route for administration among all the route that have been explored for systemic delivery of drugs via various pharmaceutical products of different dosage forms. The reasons that the oral route has achieved such popularity may be in part attributed to its ease of administration as well as the traditional belief that by oral administration the drug is well absorbed as the food stuffs that are ingested daily. In fact, the development of a pharmaceutical product for oral delivery, irrespective of its physical form involves varying extents of optimization of dosage form characteristics within the inherent constraints of GI physiology. Therefore, a fundamental understanding of various disciplines, including GI physiology, pharmacokinetics, pharmacodynamics and formulation design are essential to achieve a systemic approach to successful development of an oral pharmaceutical dosage form. The more sophisticated a...
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