Добро пожаловать в клуб

Показать / Спрятать  Домой  Новости Статьи Файлы Форум Web ссылки F.A.Q. Логобург    Показать / Спрятать

       
Поиск   
Главное меню
ДомойНовостиСтатьиПостановка звуковФайлыДефектологияКнижный мирФорумСловарьРассылкаКаталог ссылокРейтинг пользователейЧаВо(FAQ)КонкурсWeb магазинШкольникамКарта сайта

Поздравляем!
Поздравляем нового Логобуржца tatbocman со вступлением в клуб!

Реклама

КНИЖНЫЙ МИР

Influence of piperin on pioglitazone metabolism and Pk/Pd:Diabetes   Fahmeeda Begum,Reddy Sunil and Koppula Rajitha

Influence of piperin on pioglitazone metabolism and Pk/Pd:Diabetes

80 страниц. 2014 год.
LAP Lambert Academic Publishing
Several factors directly or indirectly influence the CYP activity. CYP mediated metabolism are likely to be potential candidates for drug interaction.Many drug interactions are a result of induction or inhibition of CYP enzymes. Herbal medicines that modulate intestinal and hepatic CYPs can alter the bioavailability and clearance of co –administered drugs. The diabetic patients have reduced immune system where as Piperine which have significant immunomodulatory activity. Hence, the combination has a beneficial effect in diabetic condition in view of the side effects of pioglitazone.Hence, the combination has a beneficial effect in diabetic condition, but special concern has to be observed in diabetic patients with cardiovascular complications in view of the side effects of pioglitazone. Hence the present investigation warrants further studies to find out the relevance of this interaction in human beings and postulates the exact mechanism involved.
 
- Генерация страницы: 0.04 секунд -