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Hepatoprotective potential of Leucas cephalotes (Roth) Spreng   Girish U. Sailor,Ghanshyam Parmar and A. K. Seth

Hepatoprotective potential of Leucas cephalotes (Roth) Spreng

76 страниц. 2012 год.
LAP Lambert Academic Publishing
Liver is the main organ responsible for drug metabolism and appears to be sensitive target site for substances modulating biotransformation. Despite of tremendous advances in modern medicine, hepatic disease remains a worldwide health problem. The Indian subcontinent has a glorious tradition of usage of medicinal preparations from natural herbs. Leucas Cephalotes (Roth) Spreng (Family: Labiatae or Lamiaceae) rainy season weed, traditionally used in liver disorder according to ayurveda. However, the hepatoprotective potential of plant has never been reported. Owing to the lacunae of scientific information, this study was designed to investigate the in vitro antioxidant and hepatoprotective activity of crude methanolic extract of whole plant of L. cephalotes. The results of biochemical parameters and antioxidant parameters suggested that the treatment with L. cephalotes methanolic extract enhance the recovery from CCl4 induced hepatic damaged due to its antioxidant and hepatoprotective...
 
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