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Taste Masked Azithromycin Dispersible Tablets for Pediatrics   Birjusinh J. Parmar and Pallav V. Simariya

Taste Masked Azithromycin Dispersible Tablets for Pediatrics

284 страниц. 2012 год.
LAP Lambert Academic Publishing
Oral administration is the most popular route due to ease of manufacturing, pain avoidance, accurate dosing, stability and ease of administration. However, pediatric patients find it difficult to swallow solid dosage forms like tablets and do not take their medication as prescribed. This results in high incidence of patient non- compliance and ineffective therapy. Azithromycin is a very bitter drug and it is best suited drug for the treatment of Pneumonia. In market there are lots of formulations of Azithromycin is available but it’s bitter taste leads to poor patient compliance. Moreover, it’s liquid preparation and suspension are available but they lack in stability. So, dispersible tablet of Azithromycin is formulated to overcome above problem and taste masking approach was undertaken to mask the bitter taste of the drug. So, this formulation seems to be promising formulation for Pediatrics.
 
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