160 страниц. 2012 год. LAP Lambert Academic Publishing This is an excellent piece of scientific work which shows the results of years of studies in the excipient field. This study is very valuable to engineers, pharmacists and in general, formulation scientists for the development new drug products. It specifically shows how excipients can be changed to the crystal and particle level, through processing or coprocessing to maximize their performance. The microcrystalline cellulose II is the ideal example. In this case, a polymorphic transformation occurred followed by coprocessing with a high surface are material such as fumed silica to render a high performance material with multiple pharmaceutical applications.