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Synthesis & Biological Activity s-Triazine   Deepak Kumar Basedia,B.K. Dubey and P. Valentina

Synthesis & Biological Activity s-Triazine

80 страниц. 2012 год.
LAP Lambert Academic Publishing
Triazine is the chemical species of six-membered heterocyclic ring compound with three nitrogens replacing carbon-hydrogen units in the benzene ring structure. The names of the three isomers indicate which of the carbon-hydrogen units on the benzene ring position of the molecule have been replaced by nitrogens, called 1,2,3-triazine, 1,2,4-triazine, and 1,3,5-triazine respectively. Symmetrical 1,3,5-triazine is the common. Triazines are prepared from cyanic acid amide by trimerization (1,3,5-triazine). Triazines are weak base. Triazines have much weaker resonance energy than benzene, so nucleophilic substitution is preferred than electrophilic substitution. Heterocyclics bearing a symmetrical s-triazines or 1,3,5-triazines moieties, represent an interesting class of compounds possessing a wide spectrum of biological activities such as anti-cancer, antiviral, fungicidal , insecticidal, bactericidal, herbicidal and antimicrobial, antimalarial agents. They also find applications as...
 
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