Добро пожаловать в клуб

Показать / Спрятать  Домой  Новости Статьи Файлы Форум Web ссылки F.A.Q. Логобург    Показать / Спрятать

       
Поиск   
Главное меню
ДомойНовостиСтатьиПостановка звуковФайлыКнижный мирФорумСловарьРассылкаКаталог ссылокРейтинг пользователейЧаВо(FAQ)КонкурсWeb магазинКарта сайта

Поздравляем!
Поздравляем нового Логобуржца lanna2010 со вступлением в клуб!

Реклама

КНИЖНЫЙ МИР

Pyrrolo-benzodiazepine class of Privileged Medicinal Scaffolds   Sumitra Nain,Prof. D. Kishore and Prof. B. P. Nagori

Pyrrolo-benzodiazepine class of Privileged Medicinal Scaffolds

76 страниц. 2011 год.
LAP Lambert Academic Publishing
On account of the wide range of the biological properties displayed by benzodiazepine derived compounds, benzodiazepine scaffold have been considered among the most important privileged structures for drug discovery. The development of novel biological materials based on the privileged structure is an intense area of research. Global efforts are underway to develop chemotherapeutic agentsThe main thrust of work in the area of additional fused heterocyclic rings is stimulated by the isolation of a series of antitumor antibiotics such as anthramycin, sibiromycin, tomaymycin, prothacarin, chicamycins A,B and neothramycins A,B (to mention a few), from the pyrrolo[2,1-c][1,4]-benzodiazepine class of compounds These biosynthetically derived materials are well known for inhibiting DNA replication on account of the formation of DNA – antibiotic adduct .
 
- Генерация страницы: 0.04 секунд -