Добро пожаловать в клуб

Показать / Спрятать  Домой  Новости Статьи Файлы Форум Web ссылки F.A.Q. Логобург    Показать / Спрятать

       
Поиск   
Главное меню
ДомойНовостиСтатьиПостановка звуковФайлыКнижный мирФорумСловарьРассылкаКаталог ссылокРейтинг пользователейЧаВо(FAQ)КонкурсWeb магазинКарта сайта

Поздравляем!
Поздравляем нового Логобуржца irina_vp со вступлением в клуб!

Реклама

КНИЖНЫЙ МИР

Drug Interaction and Biological Studies of Amantadine Derivatives   Amir Haider

Drug Interaction and Biological Studies of Amantadine Derivatives

224 страниц. 2012 год.
LAP Lambert Academic Publishing
Amantadine an antiviral, antiparkinsonian drug has cage like basic structure it is a colorless, crystalline compound with a camphor-like odor. The interactions of amantadine with ACE-inhibitors, cephalosporins, essential and trace elements, H1-receptor antagonists, H2-receptor antagonists, NSAIDs and quinolones was investigated in 0.1 N HCl. Amantadine complexes were synthesized with all interacting drugs and characterized by UV, FTIR, 1H-NMR and mass spectroscopy. The energy minimization study was carried out to determine the binding site of amantadine and along with these studies, metal complexes of amantadine with (Mn, Fe, Cu, Zn, Ca, Mg, Cr, Co, Ni, and Cd) were synthesized. The structures of these complexes were confirmed by IR, NMR, CHN elemental analysis and AA spectroscopy. Antiviral studies of amantadine-drug complexes evaluated through National institute of Infectious Diseases, USA in Southern Research Institute Maryland, USA. Against Biodefence viruses (Rift Valley Fever,...
 
- Генерация страницы: 0.02 секунд -