84 страниц. 2013 год. LAP Lambert Academic Publishing Erythromycin producing bacteria Saccharopolyspora erythraea strain MTCC No. 1103 was purchased from MTCC, Chandigarh. Sporulation of this bacteria was done on Oat meal Agar medium at a temperature of about 30?C. Optimization of the fermentation conditions was performed with different parameter,like temperature, pH, time etc. Fermentative production of erythromycin gave best results with a temperature of 30?C at a pH of 7.5 in 5 days. Further research works are going on process optimization with shake flask & bioreactors.