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Molecular Characterizations of Fanconi Anemia Type A (FANCA) gene   Ream Mohamed,Abdel Rahim Muddathir and Imad Fadl- Elmula

Molecular Characterizations of Fanconi Anemia Type A (FANCA) gene

108 страниц. 2014 год.
Scholars' Press
Fanconi anemia (FA) is autosomal recessive disorder. Molecular study of FA revealed that there are 15 genetic subtypes groups with FANCA gene being the most frequent. The rate of successful cytogenetic cell culture varies with the specific type of disease. Many factors can affect the cytogenetic cell culture and the successful appearance of metaphase. The determination of the amount of blood uses in cytogenetic cell culture is important to obtain excellent metaphase. The highlight of the book lies on identification and diagnosis of Fanconi anemia among aplastic anemia patients with Special emphasis on identification of FANCA gene mutations. The book also improves the chromosomal breakage test and reduces lymphocyte cell culture failure. The book is extremely useful for medical laboratory students and researchers working in hematology. Postgraduate students would find this book informative and handy.
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