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E.coli serotype and some Cytokines associated with UC and IBD patients   Awatif H. Issa,Ali R. Hasim and Saad S. Hamim

E.coli serotype and some Cytokines associated with UC and IBD patients

140 страниц. 2012 год.
LAP Lambert Academic Publishing
Irritable Bowel Syndrome and Inflammatory Bowel Diseases , including Crohn's disease and Ulcerative colitis, are two of the leading causes of chronic intestinal conditions in the world. Ulcerative colitis as an Inflammatory bowel disease is characterized by strong activation of the mucosa associated immune system due to a complex interaction of genetic, immunological and environmental factors .It is well established that the composition of the intestinal microbial flora has an impact on host immunity and influences the coarse of mucosal inflammation .Several immunological mucosal abnormalities have been described in ulcerative colitis patients? and these can be grouped into those that involve the epithelial barrier, those that involve the innate immune response (nonspecific defense against pathogens by phagocytes, dendritic cells). Although IBDS was seen as a complex biopsychological condition in which a number of major mechanisms at the central and peripheral level interact...
 
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